Research in the Arnold group focuses on evolutionary protein design methods (1,2) and using the results of laboratory evolution experiments to elucidate principles of biological design.
We generate novel and useful enzymes and organisms for applications in medicine, neurobiology, chemical synthesis and alternative energy. We also construct entire synthetic families of enzymes and other proteins in order to study structure-function relationships free from constraints of natural selection.
This research requires contributions from many disciplines, including chemistry, bioengineering, biochemistry, molecular biology, microbiology, chemical engineering, chemistry and applied physics.Follow @francesarnold
Fluorescent voltage sensor for neuronal activity
Our new P450 carbenoid/nitrenoid transfer biocatalysts to be distributed by Strem
Why Reprogramming Tiny Life Could Reap Rich Rewards
Wang et al., Angewandte Chemie Communications, early view on-line publication May 5, 2014
Claire Bedbrook (grad) and Arde Boghossian (postdoc) awarded NIH NRSA fellowships
Scott McIsaac (postdoc) awarded a Life Sciences Research Foundation fellowship
2014 National Inventors Hall of Fame
Nikki Peck (grad) and Jane Wang (postdoc) win the Dow Sustainability Innovation Student Challenge Grand Prize 2013
P450-Catalyzed Cyclopropanation and C-H Amination
2011 National Medal of Technology & Innovation
Sex, Evolution, and Innovation: Frances H. Arnold TEDxUSC May, 2012